COAGULATION CASCADE---MNEMONICS

COAGULATION CASCADE/CLOTTING FACTORS --- MNEMONICS

Clotting factors are substances in the blood that act in 

sequence to stop bleeding by forming a clot.

Here's a mnemonic to help you remember them.

I Fibrinogen

II Prothrombin

III Tissue factor

IV Calcium

V Proaccelerin, Labile factor

VI  Unassigned – Old name of Factor Va

 
VII Stable factor, proconvertin

VIII Antihemophilic factor A

IX Antihemophilic factor B or Christmas factor

X Stuart-Prower factor

XI Plasma thromboplastin antecedent

XII Hageman factor

XIII Fibrin-stabilizing factor

Mnemonics:-

"Fresher's Party Tonight, Come Let's Sing And Call Seniors, Please Have Fun"

"Foolish People Try Climbing Long Slopes After Christmas, Some People Have Fallen"

"Fit Pants, Tight Collars, Loose American Shirts Are Cool Says Pretty Heroine Farah"


Here is how you draw the coagulation cascade:-

Intrinsic pathway is activated by subendothelial collagen.

Extrinsic pathway is activated by tissue thromboplastin.

Another mnemonic:
1972 WEPT

1972: Factors 10, 9, 7 & 2
W: Warfarin
E: Extrinsic
PT: Prothrombin Time

Factors X, IX, VII, II are Vitamin K dependent.
Warfarin acts on extrinsic pathway, prothrombin time used to check it.

Heparin acts on intrinsic pathway, partial thromboplastin time is used to check it.

Here is one MNEMONIC for hemophilia.
Remember in hemophilia, bleeding time is normal, PTT is increased.